Needle-less® Serum
Experience smoother, firmer, and deeply hydrated skin—no injections required. This multitasking serum combines our proprietary CeraPep™ Technology with targeted peptides, ceramides, and sodium hyaluronate to visibly refine texture, calm visible redness, and support a healthy-looking skin barrier. It’s a simplified solution that helps skin look more radiant, balanced, and youthful.
- Visibly softens the look of fine lines and wrinkles
- Improves the appearance of firmness and elasticity
- Energizes dull-looking skin for a refreshed appearance
- Helps reduce visible redness and soothe sensitive-looking skin
4 Reasons Everyone Loves Needle-less® Serum
1. Cosmo’s “Best Peptide Serum”
This serum works. But don't take our word for it—Cosmopolitan named it the "Best Peptide Serum" in 2023.
3. Visibly Diminishes Fine Lines
Enriched with potent actives clinically proven to visibly improve the look of fine lines and wrinkles around the mouth, eyes, and forehead.
2. Dramatic Anti-aging Results You Can See
This active-packed serum is loaded with anti-aging superstars like Hyaluronic Acid, Niacinamide, and our proprietary Cerapep® Technology: a revolutionary blend of restorative peptides & ceramides.
4. Brighten the Look of Pigmentation
Niacinamide strengthens the skin’s moisture barrier, while improving the look of pigmentation and pore appearance.
CRUELTY
FREE
DERMATOLOGIST
RECOMMENDED
SULFATE
FREE
PARABEN
FREE
GLUTEN
FREE
FRAGRANCE
FREE
Dramatic Anti-aging Results
You Can See After 6 Weeks
94%
saw healthier-looking skin
91%
had firmer-feeling skin
94%
said skin felt smoother
Based on a six-week independent consumer panel
Before and After 60 Days Of Use
When used as directed. Unedited and not retouched. Results may vary.
Skin Concerns
Redness
Firmness
Wrinkles
Dryness
Post Procedure
Skin Types
Normal
Dry
Combination
Oily
Meet Our Dermatologists
Dr. Ariana Eginli
MD, FAAD
Dr. Ariana Eginli is a practicing board-certified Dermatologist in Southern California, who is skilled in treating patients with complex dermatologic conditions, cosmetics, and hair and scalp disorders. She strives to educate her patients and make them feel comfortable in their own skin.
HER FAVORITE DRM PRODUCT:Vitamin C E + F
I start every morning with the vitamin c e + f, which work synergistically to protect my skin from photoaging caused by UV light and pollution. It absorbs in my skin so well and does not leave it feeling irritated or greasy. It is a great base before applying moisturizer, sunscreen and makeup.
OUR STORY
Science-Backed Skincare, Simplified.
DRMTLGY was born of the belief that evidence-based, dermatological skincare should be available to everyone. With a rich, 20-year history in skincare manufacturing and deep roots in the dermatology community, we saw first-hand that skincare companies are overcharging their customers for medical grade ingredients.
This is what Medical Grade means to us:
We partnered with world-class chemists and expert dermatologists to create proprietary formulas with the best of ingredients. We committed to combining the art of formulation with the science of skin because we believe everyone should have access to safe, effective skincare—without unnecessary markups.
After more than a decade of extensive research, clinical testing, and physician feedback, we’re proud to offer a diverse selection of more than 40 clinically effective products for all skin types, tones, concerns, and ages. To date, we’ve transformed over 4 million skincare routines—and we’re just getting started.
Clinically Effective Ingredients, Delivered
We follow the strictest protocols to ensure every product we create is dermatologist-backed, safe for skin, and does what it says it will.
Rooted in Research—Always.
No shade on celebrities, but we prefer our skincare to be rooted in research. Our products are formulated in partnership with expert chemists, tested rigorously in the lab, and approved by our board of certified dermatologists before they ever hit your doorstep.
Meet our Board of Dermatologists
Our board of renowned dermatologists brings together years of expertise in skincare, research, and medical innovation. With a shared commitment to advancing dermatological science, they play a crucial role in developing and refining our formulations. Get to know the experts shaping the future of skincare.
Dr. Ariana Eginli
MD, FAAD
Dr. Ariana Eginli is a practicing board-certified Dermatologist in Southern California, who is skilled in treating patients with complex dermatologic conditions, cosmetics, and hair and scalp disorders. She strives to educate her patients and make them feel comfortable in their own skin.
Dr. Brittany Oliver
MD, FAAD
Dr. Oliver is a board-certified dermatologist practicing in the Kansas City metro area. Recognized as a Castle Connolly Rising Star in 2023 and 2024, she is passionate about delivering individualized care to diverse patients of all ages and backgrounds.
Dr. Marisa Garshick
MD, FAAD
Selected as New York SuperDoctors in 2021, she has a passion for being able to improve patient’s quality of life and loves to help her patients look and feel their best. She previously worked for the Dr. Oz Show and has been featured in many publications including Woman’s Health and Elle.
OUR MISSION
No one should struggle with their skin—or their confidence—and real solutions can change everything.
We believe skincare is more than self-care—it’s a lifeline when your skin feels like your biggest challenge. Whether it’s acne, dark spots, sensitivity, or signs of aging, we know how much problem skin can impact your confidence and how you show up in the world. That’s why we create dermatologist-grade, clinically proven skincare that targets real concerns with compassion, precision, and science. Because the moment you see your skin change is the moment you start to feel like yourself again. And we believe everyone deserves to feel confident in their own skin.
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